rs7133365
This is a downstream gene variant variant in the PDZRN4 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
brain attribute
van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele A
OR 8.65
p 5.0e-18
N 33,748
Large GWAS
European
cerebral cortex area attribute
Shadrin AA et al. “Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.” Neuroimage 244:118603 (2021)
Allele A
OR —
p 2.0e-10
N 35,657
Large GWAS
European
About PDZRN4
Predicted to enable zinc ion binding activity. [provided by Alliance of Genome Resources, Jul 2025]
View all PDZRN4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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