rs71482305

This variant is located in the NOC3L gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

ascending aorta diameter

Pirruccello JP et al. “Deep learning enables genetic analysis of the human thoracic aorta.” Nature Genetics 54(1):40-51 (2022)

Allele C

OR —

β 0.079

p 6.0e-23

N 38,694

Large GWAS

European

Pirruccello JP et al. “The Genetic Determinants of Aortic Distention.” Journal of the American College of Cardiology 81(14):1320-1335 (2023)

Allele C

OR 0.08

p 5.0e-22

N 38,372

Large GWAS

European, NR

About NOC3L

Enables RNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to act upstream of or within fat cell differentiation. Located in mitochondrion; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all NOC3L variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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