rs71627581

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking initiation

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele A

OR 0.01

p 4.0e-28

N 3,382,012

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

body mass index

Huang J et al. “Genomics and phenomics of body mass index reveals a complex disease network.” Nature Communications 13(1):7973 (2022)

Allele G

OR 0.02

p 3.0e-17

N 1,122,049

Large GWAS

European

smoking behavior trait

Wootton RE et al. “Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.” Psychological Medicine 50(14):2435-2443 (2020)

Allele G

OR 0.02

p 2.0e-9

N 462,690

Large GWAS

European

prostate specific antigen amount

Hoffmann TJ et al. “Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups.” Nature Genetics 57(2):334-344 (2025)

Allele A

OR 0.02

p 3.0e-9

N 392,522

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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