rs7195287

This variant is located in the PRSS33 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

eosinophil count

Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)

Allele G

OR 0.03

p 3.0e-15

N 172,275

Large GWAS

European

About PRSS33

Predicted to enable serine-type endopeptidase activity. Involved in proteolysis. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all PRSS33 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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