rs724577
This variant is located in the LCORL gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body height
Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele A
OR 0.06
p 6.0e-149
N 472,730
Large GWAS
East Asian
N'Diaye A et al. “Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.” Plos Genetics 7(10):e1002298 (2011)
Allele A
OR 0.07
p 1.0e-15
N 20,427
Large GWAS
multi-ancestry
birth weight
Yang XL et al. “Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis.” Frontiers in Genetics 10:947 (2019)
Allele A
OR 0.04
p 7.0e-17
N 182,902
Large GWAS
European
Horikoshi M et al. “New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.” Nature Genetics 45(1):76-82 (2013)
Allele A
OR 0.04
p 5.0e-11
N 26,836
Large GWAS
European
body height at birth
Yang XL et al. “Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis.” Frontiers in Genetics 10:947 (2019)
Allele A
OR 0.05
p 4.0e-16
N 182,902
Large GWAS
European
About LCORL
This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
View all LCORL variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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