rs726288

This is a intron variant variant in the SFTPD gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

rheumatoid arthritis

Okada Y et al. “Genetics of rheumatoid arthritis contributes to biology and drug discovery.” Nature 506(7488):376-381 (2014)

Allele T

OR 1.22

p 9.0e-9

N 79,799

Large GWAS

multi-ancestry

About SFTPD

The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]

View all SFTPD variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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