rs72709458
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
prostate carcinoma
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.13
p 4.0e-47
N 573,692
Major Consortium StudyLarge GWAS
multi-ancestry
glioblastoma multiforme
Kinnersley B et al. “Genome-wide association study identifies multiple susceptibility loci for glioma.” Nature Communications 6:8559 (2015)
Allele T
OR 1.68
p 6.0e-24
N 9,218
Large GWAS
European
uterine fibroid
Gallagher CS et al. “Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.” Nature Communications 10(1):4857 (2019)
Allele T
OR 0.10
p 5.0e-21
N 244,324
Large GWAS
European
postinflammatory pulmonary fibrosis
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.19
p 3.0e-14
N 444,066
Major Consortium StudyLarge GWAS
European
nontoxic goiter
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.12
p 1.0e-13
N 446,122
Major Consortium StudyLarge GWAS
European
sex hormone-binding globulin measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele C
OR 0.01
p 2.0e-9
N 368,929
Large GWAS
European
Menorrhagia
Gallagher CS et al. “Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.” Nature Communications 10(1):4857 (2019)
Allele T
OR 1.13
p 2.0e-8
N 220,759
Large GWAS
European
uterine fibroid, Menorrhagia
Gallagher CS et al. “Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.” Nature Communications 10(1):4857 (2019)
Allele T
OR 1.16
p 4.0e-8
N 202,580
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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