rs72734546

This is a downstream gene variant variant in the UBE2Q2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

glomerular filtration rate

Lee DJ et al. “Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants.” Kidney Research and Clinical Practice 43(3):299-312 (2024)

Allele T

OR 0.43

p 6.0e-9

N 58,406

Large GWAS

East Asian

About UBE2Q2

Enables ubiquitin-protein transferase activity. Involved in protein K48-linked ubiquitination. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all UBE2Q2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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