rs72770483

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

urinary metabolite measurement

Schlosser P et al. “Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.” Nature Genetics 52(2):167-176 (2020)

Allele G

OR 1.15

p 7.0e-30

N 1,221

Large GWAS

myo-inositol measurement

Schlosser P et al. “Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.” Nature Genetics 55(6):995-1008 (2023)

Allele G

OR 1.16

p 8.0e-30

N 1,618

Large GWAS

European

Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)

Allele G

OR 0.19

p 2.0e-10

N 8,193

Large GWAS

European

gut microbiome measurement

Dekkers KF et al. “Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation.” Nature Genetics 58(3):540-549 (2026)

Allele T

OR 0.21

p 7.0e-20

N 16,017

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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