rs72781632
This is a intron variant variant in the UBXN2A gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
feeling miserable measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele A
OR 5.53
p 3.0e-8
N 376,097
Large GWAS
European
About UBXN2A
Predicted to enable ubiquitin binding activity. Involved in negative regulation of ERAD pathway and positive regulation of protein catabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all UBXN2A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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