rs72898946

This is a intron variant variant in the FAF1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gestational age

Solé-Navais P et al. “Genetic effects on the timing of parturition and links to fetal birth weight.” Nature Genetics 55(4):559-567 (2023)

Allele C

OR 0.46

p 2.0e-9

N 195,555

Large GWAS

European

About FAF1

Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]

View all FAF1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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