rs72934505
This is a downstream gene variant variant in the NBEAL1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
white matter hyperintensity measurement
Persyn E et al. “Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.” Nature Communications 11(1):2175 (2020)
Allele T
OR 6.79
p 4.0e-13
N 45,204
Large GWAS
multi-ancestry
Verhaaren BF et al. “Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.” Circulation. Cardiovascular Genetics 8(2):398-409 (2015)
Allele T
OR —
p 5.0e-8
N 21,079
Large GWAS
multi-ancestry
About NBEAL1
Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytosol and membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all NBEAL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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