rs72934583
This is a intron variant variant in the NBEAL1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hypertension, white matter hyperintensity measurement
Sargurupremraj M et al. “Cerebral small vessel disease genomics and its implications across the lifespan.” Nature Communications 11(1):6285 (2020)
Allele T
OR —
p 5.0e-12
N 48,524
Large GWAS
multi-ancestry
white matter hyperintensity measurement
Sargurupremraj M et al. “Cerebral small vessel disease genomics and its implications across the lifespan.” Nature Communications 11(1):6285 (2020)
Allele T
OR 0.06
p 1.0e-12
N 48,524
Large GWAS
multi-ancestry
Armstrong NJ et al. “Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.” Stroke 51(7):2111-2121 (2020)
Allele T
OR 0.05
p 1.0e-9
N 18,226
Large GWAS
multi-ancestry
About NBEAL1
Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytosol and membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all NBEAL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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