rs72939007
This variant is located in the SPAG16 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
puberty onset measurement
Vicuña L et al. “Joint models reveal genetic architecture of pubertal stage transitions and their association with BMI in admixed Chilean population.” Human Molecular Genetics 33(19):1660-1670 (2024)
Allele T
OR 0.80
p 4.0e-8
N 211
Small GWAS
Hispanic or Latin American
About SPAG16
Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008]
View all SPAG16 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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