rs72977127
This is a downstream gene variant variant in the AGAP1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
thalamus volume
Elvsåshagen T et al. “The genetic architecture of the human thalamus and its overlap with ten common brain disorders.” Nature Communications 12(1):2909 (2021)
Allele C
OR 0.06
p 3.0e-10
N 30,114
Large GWAS
European
About AGAP1
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
View all AGAP1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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