rs72990858
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele A
OR 0.01
p 3.0e-21
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
neuroblastoma
McDaniel LD et al. “Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.” Plos Genetics 13(5):e1006787 (2017)
Allele G
OR 1.69
p 1.0e-13
N 6,303
Large GWAS
multi-ancestry
educational attainment
Okbay A et al. “Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.” Nature Genetics 54(4):437-449 (2022)
Allele A
OR 0.01
p 7.0e-11
N 3,037,499
Large GWAS
European
smoking status measurement
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele A
OR 0.01
p 2.0e-10
N 1,359,002
Large GWAS
European
age at first sexual intercourse measurement
Mills MC et al. “Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.” Nature Human Behaviour 5(12):1717-1730 (2021)
Allele G
OR 0.02
p 9.0e-10
N 397,338
Large GWAS
European
self reported educational attainment
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.01
p 4.0e-9
N 1,311,438
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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