rs72999634

This variant is located in the CHD1L gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

HIV viral set point measurement

Awada A et al. “Multi-ancestry GWAS identifies variants in a zinc finger gene cluster as novel regulators of HIV control.” The Journal of Infectious Diseases (2026)

Allele G

OR 0.28

p 1.0e-8

N 10,723

Large GWAS

multi-ancestry

About CHD1L

This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers. [provided by RefSeq, Feb 2017]

View all CHD1L variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…