rs7309727
This is a intron variant variant in the TMEM132D gene.
▶Research that mentions this SNP (1)
▶Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non‐synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopmentReviewMònica Gratacòs et al.(2009)· American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
This is a comprehensive review of genetic and epigenetic studies of panic disorder in the post-GWAS era. The review summarizes GWAS findings including associations at TMEM132D (rs7309727, rs11060369, p=1.2×10⁻⁷), GLRB (rs78726293, rs19126060, p=3.3-3.9×10⁻⁸; rs17035816, rs7688285), BDKRB2 (p=1.3×10⁻⁵), and SMAD1 (rs144783209, p=3.10×10⁻⁷), while discussing limitations and the need for larger sample sizes. The review also covers rare variant association studies (RVAS) and epigenome-wide association studies (EWAS) of panic disorder, highlighting candidate genes such as DGKH and PLA2G4E from RVAS, and epigenetic markers in HECA, CFAP46, and IL1R1 from EWAS.
About TMEM132D
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM132D variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…