rs73225858
This variant is located in the BMP1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
coronary artery calcification
Gummesson A et al. “A genome-wide association study of imaging-defined atherosclerosis.” Nature Communications 16(1):2266 (2025)
Allele T
OR 0.08
p 4.0e-8
N 26,000
Large GWAS
European
▶ClinVar annotation
Benign★☆☆☆
1 submitterAbout BMP1
This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]
View all BMP1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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