rs73239280

This is a regulatory region variant variant in the TNFAIP8 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

lymphocyte count

Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)

Allele A

OR —

p 7.0e-39

N 643,370

Large GWAS

multi-ancestry

About TNFAIP8

Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in positive regulation of apoptotic process. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all TNFAIP8 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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