rs73375428

This is a intron variant variant in the CCDC146 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

amyloid-beta measurement

Kim HR et al. “Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population.” Alzheimer's Research & Therapy 13(1):117 (2021)

Allele G

OR 0.53

p 3.0e-8

N 1,190

Large GWAS

East Asian

About CCDC146

Involved in spermatid development. Located in several cellular components, including microtubule organizing center; midbody; and sperm flagellum. Implicated in spermatogenic failure 94. [provided by Alliance of Genome Resources, Jul 2025]

View all CCDC146 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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