rs73596816

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GWAS Catalog Trait Associations (44)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

lipoprotein A measurement

Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.75
p —
N 284,044
Major Consortium StudyLarge GWAS
multi-ancestry
Mack S et al. “A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.” Journal of Lipid Research 58(9):1834-1844 (2017)
Allele A
OR 11.20
p 2.0e-18
N 13,781
Meta-analysisLarge GWAS
European
Jeon S et al. “Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups.” Gigascience 13 (2024)
Allele A
OR 1.08
p 5.0e-39
N 1,818
Large GWAS
East Asian
Liu Y et al. “A genome-wide association study on lipoprotein (a) levels and coronary artery disease severity in a Chinese population.” Journal of Lipid Research 60(8):1440-1448 (2019)
Allele A
OR 0.86
p 1.0e-22
N 1,402
Large GWAS
East Asian

VLDL particle size

Davyson E et al. “Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids.” Biological Psychiatry 94(8):630-639 (2023)
Allele A
OR 0.12
p 1.0e-23
N 88,329
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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