rs7374732
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
visceral:subcutaneous adipose tissue ratio
body mass index, visceral:subcutaneous adipose tissue ratio
▶Research that mentions this SNP (1)
▶Genome‐Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex‐Specific Adiposity Loci in Mexican AmericansAssociationN=1,417Chuan Gao et al.(2018)· Obesity
This genome-wide association study (GWAS) in 1,417 Mexican Americans identified six loci with genome-wide significant associations with fat deposition phenotypes (visceral and subcutaneous adipose tissue). The strongest signal was rs2185405 in GLIS3 associated with visceral adipose tissue (P=1.98×10⁻⁸), with carriers of the minor allele showing 19.91 cm² less visceral fat. Sex-stratified analyses revealed SRFBP1 and SNX13 loci with male-specific associations, and SNP-sex interaction analyses identified significant variants in TMCC1, PAPPA2, and TBX15.
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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