rs7431106
This is a upstream gene variant variant in the IP6K1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
post-traumatic stress disorder
Nievergelt CM et al. “Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.” Nature Genetics 56(5):792-808 (2024)
Allele A
OR 7.94
p 2.0e-15
N 1,280,933
Large GWAS
multi-ancestry
About IP6K1
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]
View all IP6K1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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