rs745943253
This variant is located in the PLSCR1 gene.
▶ClinVar annotation
About PLSCR1
This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses. [provided by RefSeq, May 2022]
View all PLSCR1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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