rs748431
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
coronary artery disease
Jordà P et al. “Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases.” Npj Genomic Medicine 10(1):65 (2025)
Allele G
OR 7.36
p 2.0e-13
N 310,368
Large GWAS
European
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele G
OR 0.02
p 4.0e-8
N 640,258
Large GWAS
European, East Asian
Klarin D et al. “Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.” Nature Genetics 49(9):1392-1397 (2017)
Allele G
OR 1.05
p 3.0e-8
N 120,286
Major Consortium StudyLarge GWAS
multi-ancestry
large artery stroke
Mishra A et al. “Stroke genetics informs drug discovery and risk prediction across ancestries.” Nature 611(7934):115-123 (2022)
Allele G
OR 1.05
p 3.0e-9
N 1,241,207
Large GWAS
European
myocardial infarction
Hartiala JA et al. “Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.” European Heart Journal 42(9):919-933 (2021)
Allele G
OR 1.04
p 4.0e-8
N 639,221
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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