rs7555748
This variant is located in the SHE gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
interleukin 6 receptor subunit alpha measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele C
OR 0.58
p 3.0e-15
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
About SHE
Predicted to enable phosphotyrosine residue binding activity. [provided by Alliance of Genome Resources, Jul 2025]
View all SHE variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…