rs7571789

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cartilage thickness measurement

Faber BG et al. “The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.” Ebiomedicine 95:104759 (2023)

Allele T

OR 0.09

p 3.0e-50

N 50,745

Meta-analysisLarge GWAS

European

grip strength measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele C

OR 0.01

p 2.0e-18

N 394,642

Large GWAS

European

osteoarthritis, hip

Tachmazidou I et al. “Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.” Nature Genetics 51(2):230-236 (2019)

Allele T

OR 1.09

p 3.0e-14

N 393,873

Major Consortium StudyLarge GWAS

European

alpha angle measurement

Faber BG et al. “A Genome-Wide Association Study Meta-Analysis of Alpha Angle Suggests Cam-Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults.” Arthritis & Rheumatology (hoboken, N.j.) 75(6):900-909 (2023)

Allele T

OR —

β 0.040

p 8.0e-9

N 44,214

Meta-analysisLarge GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…