rs757613781

This variant is located in the FCGR2B gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About FCGR2B

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

View all FCGR2B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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