rs759284466

This variant is located in the STK11 gene.

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ClinVar annotation

Conflicting Classifications
8 submitters3 publications

Hereditary cancer-predisposing syndrome; not specified; not provided; Peutz-Jeghers syndrome; Breast and/or ovarian cancer; STK11-related disorder

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About STK11

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers. [provided by RefSeq, May 2022]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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