rs7594321

This is a intron variant variant in the DNER gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

FEV/FVC ratio, pulmonary function measurement, smoking behavior trait

Hancock DB et al. “Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.” Plos Genetics 8(12):e1003098 (2012)

Allele T

OR —

β 0.015

p 3.0e-9

N 50,047

Meta-analysisLarge GWAS

European

About DNER

Predicted to enable Notch binding activity. Involved in central nervous system development. Located in dendrite; early endosome; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all DNER variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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