rs760060325

This variant is located in the RPS6KA4 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆
1 submitter

not specified

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About RPS6KA4

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

View all RPS6KA4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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