rs7603972

This is a upstream gene variant variant in the CARF gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

white matter hyperintensity measurement

Sargurupremraj M et al. “Cerebral small vessel disease genomics and its implications across the lifespan.” Nature Communications 11(1):6285 (2020)

Allele A

OR 0.07

p 2.0e-13

N 48,454

Large GWAS

European

About CARF

Enables DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in cellular response to calcium ion. Predicted to be located in granular component. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all CARF variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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