rs76181804

This is a regulatory region variant variant.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

asthma

Zhou W et al. “Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.” Cell Genomics 2(10):100192 (2022)

Allele G

OR 0.06

p 3.0e-15

N 1,800,785

Meta-analysisLarge GWAS

multi-ancestry

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele G

OR 0.08

p 9.0e-10

N 625,448

Large GWAS

multi-ancestry

Zhu Z et al. “Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.” The European Respiratory Journal 54(6) (2019)

Allele G

OR 1.05

p 3.0e-8

N 394,283

Large GWAS

multi-ancestry

Han Y et al. “Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.” Nature Communications 11(1):1776 (2020)

Allele G

OR 1.07

p 3.0e-13

N 303,859

Large GWAS

European

eosinophil count

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele A

OR 0.05

p 6.0e-22

N 447,598

Major Consortium StudyLarge GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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