rs7618915
This variant is located in the PPM1M gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bipolar disorder
Chen DT et al. “Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.” Molecular Psychiatry 18(2):195-205 (2013)
Allele G
OR —
p 3.0e-10
N 14,755
Meta-analysisLarge GWAS
multi-ancestry
About PPM1M
Predicted to enable [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity and manganese ion binding activity. Predicted to be involved in protein dephosphorylation and signal transduction. Predicted to be located in nucleus. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all PPM1M variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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