rs76298292

This is a intron variant variant in the SH2D4B gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement, tobacco smoke exposure measurement

Stickley SA et al. Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy. The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)
Allele G
OR
β 2.590
p 4.0e-8
N 693
Small GWAS
multi-ancestry

About SH2D4B

Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all SH2D4B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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