rs763092306
This is a protein-altering variant in the NEUROD1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Glycosuria
Benonisdottir S et al. “Sequence variants associating with urinary biomarkers.” Human Molecular Genetics 28(7):1199-1211 (2019)
Allele T
OR 23.74
p 1.0e-10
N 141,621
Large GWAS
European
About NEUROD1
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]
View all NEUROD1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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