rs763936875

This variant is located in the HMCN2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Barrett's esophagus

Jiang L et al. “A generalized linear mixed model association tool for biobank-scale data.” Nature Genetics 53(11):1616-1621 (2021)

Allele A

OR 1.88

p 2.0e-9

N 456,348

Large GWAS

European

About HMCN2

Predicted to enable axon guidance receptor activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules and synapse organization. Located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2025]

View all HMCN2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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