rs76560824

This is a regulatory region variant variant in the B4GALNT4 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

osteoarthritis, knee, body mass index

Zhang L et al. “A sex- and site-specific relationship between body mass index and osteoarthritis: evidence from observational and genetic analyses.” Osteoarthritis and Cartilage 31(6):819-828 (2023)

Allele T

OR —

p 9.0e-12

N 1,202,888

Large GWAS

European

body weight

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele T

OR 0.03

p 5.0e-11

N 928,679

Large GWAS

multi-ancestry

About B4GALNT4

Enables acetylgalactosaminyltransferase activity. Predicted to be located in Golgi cisterna membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all B4GALNT4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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