rs76825149

This is a intron variant variant in the PARPBP gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

prostate carcinoma

Wang A et al. “Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.” Nature Genetics 55(12):2065-2074 (2023)

Allele G

OR 1.04

p 3.0e-13

N 944,762

Large GWAS

multi-ancestry

About PARPBP

Predicted to enable DNA binding activity. Involved in negative regulation of double-strand break repair via homologous recombination. Located in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all PARPBP variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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