rs76863928

This variant is located in the HMGA1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Cho HW et al. “A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans.” Frontiers in Genetics 12:669215 (2021)

Allele T

OR 0.47

p 2.0e-22

N 5,472

Large GWAS

East Asian

About HMGA1

This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]

View all HMGA1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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