rs768770273

This variant is located in the EBI3 gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About EBI3

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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