rs76920163

This is a intron variant variant in the CHDH gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

clinical treatment

Jiang L et al. A generalized linear mixed model association tool for biobank-scale data. Nature Genetics 53(11):1616-1621 (2021)
Allele G
OR 0.46
p 2.0e-9
N 456,276
Large GWAS
European

About CHDH

The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date. [provided by RefSeq, Dec 2010]

View all CHDH variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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