rs770809590
This variant is located in the DNAH1 gene.
▶ClinVar annotation
Spermatogenic failure 18;Ciliary dyskinesia, primary, 37
View on ClinVar →About DNAH1
This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
View all DNAH1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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