rs77270337

This variant is located in the BRME1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Hodgkins lymphoma

Osman Y et al. “Functional multigenic variations associated with hodgkin lymphoma.” International Journal of Laboratory Hematology 43(6):1472-1482 (2021)

Allele A

OR —

β 0.056

p 9.0e-11

N 97

Small GWAS

Greater Middle Eastern (Middle Eastern, North African or Persian)

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ClinVar annotation

Likely Benign★☆☆☆

1 submitter

View on ClinVar →

About BRME1

Predicted to enable damaged DNA binding activity. Predicted to be involved in meiosis I; protein localization to site of double-strand break; and spermatogenesis. Predicted to be located in chromosome. Predicted to be active in site of double-strand break. [provided by Alliance of Genome Resources, Apr 2025]

View all BRME1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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