rs77291744

This is a intron variant variant in the KIF20B gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain attribute

van der Meer D et al. The genetic architecture of human cortical folding. Science Advances 7(51):eabj9446 (2021)
Allele A
OR 6.73
p 2.0e-11
N 33,748
Large GWAS
European

About KIF20B

Enables several functions, including ATP hydrolysis activity; WW domain binding activity; and plus-end-directed microtubule motor activity. Involved in positive regulation of cell population proliferation and positive regulation of cytokinesis. Located in several cellular components, including microtubule cytoskeleton; midbody; and nuclear lumen. [provided by Alliance of Genome Resources, Jul 2025]

View all KIF20B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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