rs77310623

This is a intron variant variant in the RAB32 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Abnormality of skin pigmentation

Kim B et al. “Mapping and annotating genomic loci to prioritize genes and implicate distinct polygenic adaptations for skin color.” Nature Communications 15(1):4874 (2024)

Allele A

OR 0.10

p 1.0e-13

N 48,433

Large GWAS

East Asian

About RAB32

The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this gene may be linked to leprosy. [provided by RefSeq, Dec 2015]

View all RAB32 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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