rs773107

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

self reported educational attainment

Schoeler T et al. “Participation bias in the UK Biobank distorts genetic associations and downstream analyses.” Nature Human Behaviour 7(7):1216-1227 (2023)
Allele G
OR 0.03
p 5.0e-12
N 283,749
Major Consortium StudyLarge GWAS
European

psoriasis

Zhang M et al. “Multi-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis.” Journal of Translational Medicine 23(1):133 (2025)
Allele A
OR 0.06
p 2.0e-8
N 472,819
Meta-analysisLarge GWAS
multi-ancestry
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Research that mentions this SNP (1)

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Polymorphisms in chromosome region 12q13 and their influence on age at onset of type 1 diabetes
AssociationN=1,305Espino-Paisan L. et al.(2011)· Diabetologia

This case-control study examined three SNPs (rs773107, rs2292239, rs10876864) in chromosome region 12q13 for associations with type 1 diabetes age at onset in 444 Spanish diabetic patients and 861 controls. rs773107 and rs2292239 showed significant associations with disease (p ≤0.008 and p=0.03, respectively), with early-onset patients (≤16 years) showing stronger associations than late-onset patients. Subjects with risk genotypes had disease onset 2-5 years earlier than protective allele carriers.

Traits studied:Age at onset of type 1 diabetesType 1 diabetes
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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