rs773476797
This variant is located in the IRAK4 gene.
▶ClinVar annotation
About IRAK4
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
View all IRAK4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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