rs77401305
This variant is located in the PPP1R37 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
synaptosomal-associated protein 25 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.08
p 4.0e-16
N 47,745
Large GWAS
European
Alzheimer disease, family history of Alzheimer’s disease
Willett JDS et al. “Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 21(2):e14592 (2025)
Allele A
OR —
p 2.0e-10
N 404,467
Large GWAS
multi-ancestry
About PPP1R37
Predicted to enable protein phosphatase inhibitor activity. [provided by Alliance of Genome Resources, Jul 2025]
View all PPP1R37 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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